Schedule
| Day | Game | Visitor Team | Score | Home Team | Score | Overtime | Shoot Out | Game Details |
|---|---|---|---|---|---|---|---|---|
| 3 | 10 | Buffalo Sabres | 4 | Columbus Blue Jackets | 3 | - | - | Scores |
| 5 | 30 | Chicago Black Hawks | 4 | Buffalo Sabres | 5 | True | - | Scores |
| 8 | 48 | Minnesota Wild | 4 | Buffalo Sabres | 3 | - | - | Scores |
| 10 | 63 | Dallas Stars | 3 | Buffalo Sabres | 2 | - | - | Scores |
| 12 | 72 | Utah Mammoth | 3 | Buffalo Sabres | 2 | True | True | Scores |
| 14 | 87 | Florida Panthers | 5 | Buffalo Sabres | 4 | True | - | Scores |
| 15 | 92 | Buffalo Sabres | 4 | Montreal Canadiens | 2 | - | - | Scores |
| 17 | 115 | Buffalo Sabres | 3 | Toronto Maple Leafs | 1 | - | - | Scores |
| 19 | 123 | Buffalo Sabres | 4 | Montreal Canadiens | 2 | - | - | Scores |
| 23 | 153 | Philadelphia Flyers | 0 | Buffalo Sabres | 0 | - | - | |
| 26 | 168 | Buffalo Sabres | 0 | Washington Capitals | 0 | - | - | |
| 29 | 198 | Buffalo Sabres | 0 | San Jose Sharks | 0 | - | - | |
| 31 | 208 | Buffalo Sabres | 0 | Anaheim Ducks | 0 | - | - | |
| 33 | 225 | Buffalo Sabres | 0 | Los Angeles Kings | 0 | - | - | |
| 37 | 250 | Ottawa Senators | 0 | Buffalo Sabres | 0 | - | - | |
| 39 | 264 | Columbus Blue Jackets | 0 | Buffalo Sabres | 0 | - | - | |
| 41 | 277 | Vegas Golden Knights | 0 | Buffalo Sabres | 0 | - | - | |
| 44 | 298 | Tampa Bay Lightning | 0 | Buffalo Sabres | 0 | - | - | |
| 45 | 304 | Buffalo Sabres | 0 | Chicago Black Hawks | 0 | - | - | |
| 47 | 316 | Buffalo Sabres | 0 | Dallas Stars | 0 | - | - | |
| 50 | 334 | Buffalo Sabres | 0 | Philadelphia Flyers | 0 | - | - | |
| 52 | 347 | Buffalo Sabres | 0 | Washington Capitals | 0 | - | - | |
| 53 | 364 | Buffalo Sabres | 0 | Florida Panthers | 0 | - | - | |
| 54 | 375 | Buffalo Sabres | 0 | Tampa Bay Lightning | 0 | - | - | |
| 57 | 390 | New York Rangers | 0 | Buffalo Sabres | 0 | - | - | |
| 58 | 406 | Pittsburgh Penguins | 0 | Buffalo Sabres | 0 | - | - | |
| 62 | 437 | Buffalo Sabres | 0 | Edmonton Oilers | 0 | - | - | |
| 64 | 456 | Buffalo Sabres | 0 | Calgary Flames | 0 | - | - | |
| 65 | 461 | Buffalo Sabres | 0 | Vancouver Canucks | 0 | - | - | |
| 67 | 478 | Buffalo Sabres | 0 | Seattle Kraken | 0 | - | - | |
| 71 | 504 | Edmonton Oilers | 0 | Buffalo Sabres | 0 | - | - | |
| 73 | 521 | Anaheim Ducks | 0 | Buffalo Sabres | 0 | - | - | |
| 75 | 531 | Buffalo Sabres | 0 | Ottawa Senators | 0 | - | - | |
| 76 | 538 | Calgary Flames | 0 | Buffalo Sabres | 0 | - | - | |
| 79 | 560 | Montreal Canadiens | 0 | Buffalo Sabres | 0 | - | - | |
| 81 | 581 | Los Angeles Kings | 0 | Buffalo Sabres | 0 | - | - | |
| 83 | 600 | Buffalo Sabres | 0 | Pittsburgh Penguins | 0 | - | - | |
| 84 | 611 | New Jersey Devils | 0 | Buffalo Sabres | 0 | - | - | |
| 86 | 624 | Detroit Red Wings | 0 | Buffalo Sabres | 0 | - | - | |
| 88 | 639 | Buffalo Sabres | 0 | Florida Panthers | 0 | - | - | |
| 91 | 660 | Buffalo Sabres | 0 | Tampa Bay Lightning | 0 | - | - | |
| 93 | 675 | Winnipeg Jets | 0 | Buffalo Sabres | 0 | - | - | |
| 94 | 685 | Buffalo Sabres | 0 | Boston Bruins | 0 | - | - | |
| 97 | 705 | Buffalo Sabres | 0 | Columbus Blue Jackets | 0 | - | - | |
| 98 | 718 | Carolina Hurricanes | 0 | Buffalo Sabres | 0 | - | - | |
| 101 | 736 | New Jersey Devils | 0 | Buffalo Sabres | 0 | - | - | |
| 103 | 743 | Colorado Avalanche | 0 | Buffalo Sabres | 0 | - | - | |
| 105 | 762 | Nashville Predators | 0 | Buffalo Sabres | 0 | - | - | |
| 107 | 783 | Montreal Canadiens | 0 | Buffalo Sabres | 0 | - | - | |
| 109 | 797 | Buffalo Sabres | 0 | New York Islanders | 0 | - | - | |
| 110 | 804 | Seattle Kraken | 0 | Buffalo Sabres | 0 | - | - | |
| 113 | 824 | Buffalo Sabres | 0 | Winnipeg Jets | 0 | - | - | |
| 116 | 846 | Buffalo Sabres | 0 | Utah Mammoth | 0 | - | - | |
| 117 | 850 | Buffalo Sabres | 0 | Vegas Golden Knights | 0 | - | - | |
| 119 | 875 | Buffalo Sabres | 0 | Colorado Avalanche | 0 | - | - | |
| 123 | 889 | New York Islanders | 0 | Buffalo Sabres | 0 | - | - | |
| 129 | 917 | Buffalo Sabres | 0 | Carolina Hurricanes | 0 | - | - | |
| 131 | 930 | Buffalo Sabres | 0 | New York Rangers | 0 | - | - | |
| 134 | 956 | Carolina Hurricanes | 0 | Buffalo Sabres | 0 | - | - | |
| 136 | 973 | Buffalo Sabres | 0 | New Jersey Devils | 0 | - | - | |
| 137 | 978 | Buffalo Sabres | 0 | Detroit Red Wings | 0 | - | - | |
| 140 | 1002 | Buffalo Sabres | 0 | Philadelphia Flyers | 0 | - | - | |
| 142 | 1017 | Ottawa Senators | 0 | Buffalo Sabres | 0 | - | - | |
| 143 | 1026 | Toronto Maple Leafs | 0 | Buffalo Sabres | 0 | - | - | |
| 146 | 1044 | Pittsburgh Penguins | 0 | Buffalo Sabres | 0 | - | - | |
| 148 | 1059 | St Louis Blues | 0 | Buffalo Sabres | 0 | - | - | |
| 150 | 1075 | New York Rangers | 0 | Buffalo Sabres | 0 | - | - | |
| 151 | 1084 | Buffalo Sabres | 0 | Ottawa Senators | 0 | - | - | |
| 153 | 1097 | Vancouver Canucks | 0 | Buffalo Sabres | 0 | - | - | |
| 156 | 1118 | Buffalo Sabres | 0 | Detroit Red Wings | 0 | - | - | |
| 158 | 1136 | Buffalo Sabres | 0 | Minnesota Wild | 0 | - | - | |
| 159 | 1146 | San Jose Sharks | 0 | Buffalo Sabres | 0 | - | - | |
| 162 | 1163 | Washington Capitals | 0 | Buffalo Sabres | 0 | - | - | |
| 164 | 1177 | Florida Panthers | 0 | Buffalo Sabres | 0 | - | - | |
| 165 | 1191 | Buffalo Sabres | 0 | New York Islanders | 0 | - | - | |
| 167 | 1196 | Buffalo Sabres | 0 | Boston Bruins | 0 | - | - | |
| 169 | 1217 | Toronto Maple Leafs | 0 | Buffalo Sabres | 0 | - | - | |
| 172 | 1242 | Buffalo Sabres | 0 | St Louis Blues | 0 | - | - | |
| 174 | 1258 | Buffalo Sabres | 0 | Nashville Predators | 0 | - | - | |
| 176 | 1266 | Boston Bruins | 0 | Buffalo Sabres | 0 | - | - | |
| 178 | 1287 | Buffalo Sabres | 0 | Toronto Maple Leafs | 0 | - | - | |
| 180 | 1296 | Tampa Bay Lightning | 0 | Buffalo Sabres | 0 | - | - | |
| 182 | 1315 | Boston Bruins | 0 | Buffalo Sabres | 0 | - | - | |
| 185 | 1339 | Detroit Red Wings | 0 | Buffalo Sabres | 0 | - | - |